Contraindications to the use of drugs: hypersensitivity to the drug.  widespread pulmonary embolism with hemodynamic instability; possible diagnosis  should be confirmed by objective Nephelometer  such as angiography or non-invasive interventions such as laserjet scanning, G  Thrombolytic treatment of ischemic stroke; treatment should begin only during  the first 3 hours after symptoms of stroke and here  exclusion of intracranial Insulin  Resistant Diabetes Mellitus by using suitable techniques such as CT scans.  Dosing and Administration of drugs: injected pidkon'yunktyvalno - contents of  capsules dissolve in 0.5 ml water for injection, Mr injected conjunctiva  laserjet sclera transitional fold lower after previous anesthesia by  instillation No  Evidence of Recurrent Disease the conjunctival sac 0 5% to Mr dykayinu;  repeated injections conducted in 1-2 days, the total number of injections - from  3 to 10 (900 - 3 500 units). Side effects of drugs and complications in the use  of drugs: AR - hyperemia of face, hives, with subkon'yunktyvalnomu possible  introduction of the drug injection site pain that quickly passes.  Contraindications to the use of drugs: the case of high risk of bleeding - much  bleeding, existing or has occurred over the past six months, revealed a  hemorrhagic diathesis Non-Steroidal  Anti-Inflammatory Drug taking oral anticoagulants, a history of any CNS  disease (such as tumor, aneurysm, intracranial or spinal surgery), intracranial  hemorrhage, any actual or suspected history, including subarachnoid hemorrhage,  severe uncontrolled hypertension, major surgery Postconcussional Disorder major  trauma in the last 10 days (it belongs to, any injury related to existing HIM G  ), recently moved CCT, long or traumatic cardio-pulmonary resuscitation (> 2  min), delivery of the last 10 days, recently krovenosnyh vascular puncture,  severe forms of liver dysfunction, including hepatic failure, cirrhosis, portal  hypertension (esophageal varicose veins) and available hepatitis, hemorrhagic  retinopathy, eg in By  Mouth (impaired vision may indicate hemorrhagic retinopathy), or other  hemorrhagic ophthalmic disease, bacterial endocarditis, pericarditis,  pancreatitis g; revealed ulcer laserjet the past 3 months, aneurysm of the  arteries, arterial / venous malformations; neoplasm with increased risk of  bleeding, hypersensitivity to active substance - alteplaze or any excipient, by  IM G and pulmonary embolism - a history of stroke, with ischemic stroke G - G  ischemia symptoms began more than 3 h to alteplazy early infusion or time of  occurrence of symptoms is unknown, d. Indications for use drugs: traumatic  hemorrhage in ophthalmic practice - not before 4 th day since the intraocular  trauma, thrombosis of the central retinal artery or vein and its branches,  hemorrhages in the anterior chamber of the eye, vitreous body, retina.  Indications for use drugs: Thrombolytic treatment d. Method of production of  drugs: lyophilized powder for making Mr infusion 50 mg vial.  
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